Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Drosophila sp. (in: flies) | mutations in wollknäuel, a UDPglucose:dolichyl-phosphate glucosyltransferase involved in N-linked protein glycosylation, disrupts Drosophila embryo development by affecting the expression of a few key gene regulators. Reduced glycosylation efficiency in wol mutant embryos triggers the unfolded protein response. As a result, phosphorylation of eIF2a is increased | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Drosophila sp. (in: flies) | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | mutations in wollknäuel, a UDPglucose:dolichyl-phosphate glucosyltransferase involved in N-linked protein glycosylation, disrupts Drosophila embryo development by affecting the expression of a few key gene regulators. Reduced glycosylation efficiency in wol mutant embryos triggers the unfolded protein response. As a result, phosphorylation of eIF2a is increased | Drosophila sp. (in: flies) | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
UDP-glucose:dolichyl-phosphate glucosyltransferase | - |
Drosophila sp. (in: flies) |
wollknäuel | - |
Drosophila sp. (in: flies) |