Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 2.4.1.117 extracted from

  • Haecker, A.; Bergman, M.; Neupert, C.; Moussian, B.; Luschnig, S.; Aebi, M.; Mannervik, M.
    Wollknauel is required for embryo patterning and encodes the Drosophila ALG5 UDP-glucose:dolichyl-phosphate glucosyltransferase (2008), Development, 135, 1745-1749.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Drosophila sp. (in: flies) mutations in wollknäuel, a UDPglucose:dolichyl-phosphate glucosyltransferase involved in N-linked protein glycosylation, disrupts Drosophila embryo development by affecting the expression of a few key gene regulators. Reduced glycosylation efficiency in wol mutant embryos triggers the unfolded protein response. As a result, phosphorylation of eIF2a is increased ?
-
?

Organism

Organism UniProt Comment Textmining
Drosophila sp. (in: flies)
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information mutations in wollknäuel, a UDPglucose:dolichyl-phosphate glucosyltransferase involved in N-linked protein glycosylation, disrupts Drosophila embryo development by affecting the expression of a few key gene regulators. Reduced glycosylation efficiency in wol mutant embryos triggers the unfolded protein response. As a result, phosphorylation of eIF2a is increased Drosophila sp. (in: flies) ?
-
?

Synonyms

Synonyms Comment Organism
UDP-glucose:dolichyl-phosphate glucosyltransferase
-
Drosophila sp. (in: flies)
wollknäuel
-
Drosophila sp. (in: flies)