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BRENDA support

Literature summary for 2.4.1.11 extracted from

  • Cammisotto, P.G.; Londono, I.; Gingras, D.; Bendayan, M.
    Control of glycogen synthase through ADIPOR1-AMPK pathway in renal distal tubules of normal and diabetic rats (2008), Am. J. Physiol. Renal Physiol., 294, F881-F889.
    View publication on PubMed

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
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Source Tissue

Source Tissue Comment Organism Textmining
renal distal tubule in distal tubular cells, adiponectin through luminal ADIPOR1 activates AMPK, leading to the inhibition of glycogen synthase. During hyperglycemia, this regulation is altered, which may explain, at least in part, the accumulation of large glycogen deposits Rattus norvegicus
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Synonyms

Synonyms Comment Organism
glycogen synthase
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Rattus norvegicus