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Literature summary for 2.4.1.11 extracted from

  • Camici, M.; DePaoli-Roach, A.A.; Roach, P.J.
    Rabbit liver glycogen synthase. Purification and comparison of the properties of glucose-6-P-dependent and glucose-6-P-independent forms of the enzyme (1984), J. Biol. Chem., 259, 3429-3434.
    View publication on PubMed

Activating Compound

Activating Compound Comment Organism Structure
glucose 6-phosphate synthase D, i.e. phosphorylated form, is glucose 6-phosphate dependent, synthase I, i.e. dephosphorylated form, is glucose 6-phosphate independent, interconversion of D and I forms and vice versa Oryctolagus cuniculus

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
85000
-
x * 85000, synthase I, SDS-PAGE Oryctolagus cuniculus
90000
-
x * 90000, synthase D, SDS-PAGE Oryctolagus cuniculus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
UDP-glucose + glycogen Oryctolagus cuniculus
-
glycogen + UDP
-
?

Organism

Organism UniProt Comment Textmining
Oryctolagus cuniculus
-
-
-

Posttranslational Modification

Posttranslational Modification Comment Organism
phosphoprotein phosphorylation of glucose-6-phosphate independent enzyme, i.e. I enzyme, results in glucose-6-phosphate dependent enzyme, i.e. D enzyme Oryctolagus cuniculus

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
Oryctolagus cuniculus
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
3
-
synthase D Oryctolagus cuniculus
11.3
-
synthase I Oryctolagus cuniculus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
UDP-glucose + glycogen
-
Oryctolagus cuniculus glycogen + UDP
-
?

Subunits

Subunits Comment Organism
? x * 85000, synthase I, SDS-PAGE Oryctolagus cuniculus
? x * 90000, synthase D, SDS-PAGE Oryctolagus cuniculus