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Literature summary for 2.4.1.102 extracted from

  • Beum, P.V.; Basma, H.; Bastola, D.R.; Cheng, P.W.
    Mucin biosynthesis: upregulation of core 2 beta 1,6 N-acetylglucosaminyltransferase by retinoic acid and Th2 cytokines in a human airway epithelial cell line (2005), Am. J. Physiol., 288, L116-124.
    View publication on PubMed
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Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens M isoform is upregulated by both all-trans retinoic acid and by IL-4/13. L-isoform is moderately upregulated by IL-4/13 but not by all-trans retinoic acid ?
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Organism

Organism UniProt Comment Textmining
Homo sapiens
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Source Tissue

Source Tissue Comment Organism Textmining
NCI-H292 cell airway epithelial cell line Homo sapiens
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information M isoform is upregulated by both all-trans retinoic acid and by IL-4/13. L-isoform is moderately upregulated by IL-4/13 but not by all-trans retinoic acid Homo sapiens ?
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 ?
additional information the M isoform of C2GnT can form all mucin glycan beta1,6-branched structures, including core 2, core 4, and blood group I antigen. The L-isoform forms only core 2 structures Homo sapiens ?
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 ?

Synonyms

Synonyms Comment Organism
C2GnT
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 Homo sapiens
core 2 beta1,6 N-acetylglucosaminyltransferase
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 Homo sapiens