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Literature summary for 2.4.1.1 extracted from

  • Polyak, M.; Varga, G.; Szilagyi, B.; Juhasz, L.; Docsa, T.; Gergely, P.; Begum, J.; Hayes, J.M.; Somsak, L.
    Synthesis, enzyme kinetics and computational evaluation of N-(beta-D-glucopyranosyl) oxadiazolecarboxamides as glycogen phosphorylase inhibitors (2013), Bioorg. Med. Chem., 21, 5738-5747.
    View publication on PubMed
Search for more literature for 2.4.1.1

Inhibitors

Inhibitors Comment Organism Structure
additional information synthesis, enzyme kinetics and computational evaluation of N-(beta-D-glucopyranosyl) oxadiazolecarboxamides as glycogen phosphorylase inhibitors, overview. The compounds have promising oral drug-like properties without any toxicity. No inhibition by N-(beta-D-glucopyranosyl)-5-(naphth-2-yl)-1,2,4-oxadiazol-3-carboxamide, N-(beta-D-glucopyranosyl)-3-(napht-2-yl)-1,2,4-oxadiazol-5-carboxamide, N-[3-(naphthalen-2-yl)-1,2-oxazole-5-carbonyl]-beta-D-glucopyranosylamine, and N-[1-(naphthalen-2-yl)-1H-1,2,3-triazole-4-carbonyl]-beta-D-glucopyranosylamine Oryctolagus cuniculus
N-(1-phenyl-1H-1,2,3-triazole-4-carbonyl)-beta-D-glucopyranosylamine
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 Oryctolagus cuniculus
N-(3-phenyl-1,2-oxazole-5-carbonyl)-beta-D-glucopyranosylamine
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 Oryctolagus cuniculus
N-(benzoylcarbamoyl)-beta-D-glucopyranosylamine
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 Oryctolagus cuniculus
N-(beta-D-glucopyranosyl)-3-(napht-1-yl)-1,2,4-oxadiazol-5-carboxamide
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 Oryctolagus cuniculus
N-(beta-D-glucopyranosyl)-3-phenyl-1,2,4-oxadiazol-5-carboxamide
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 Oryctolagus cuniculus
N-(beta-D-glucopyranosyl)-5-(napht-1-yl)-1,3,4-oxadiazole-2-carboxamide
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 Oryctolagus cuniculus
N-(beta-D-glucopyranosyl)-5-(naphth-1-yl)-1,2,4-oxadiazol-3-carboxamide
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 Oryctolagus cuniculus
N-(beta-D-glucopyranosyl)-5-(naphth-2-yl)-1,3,4-oxadiazole-2-carboxamide
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 Oryctolagus cuniculus
N-(beta-D-glucopyranosyl)-5-phenyl-1,2,4-oxadiazol-3-carboxamide
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 Oryctolagus cuniculus
N-(beta-D-glucopyranosyl)-5-phenyl-1,3,4-oxadiazole-2-carboxamide
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 Oryctolagus cuniculus
N-(naphthalene-1-carbonyl)-beta-D-glucopyranosylamine
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 Oryctolagus cuniculus
N-(naphthalene-2-carbonyl)-beta-D-glucopyranosylamine
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 Oryctolagus cuniculus
N-benzoyl-beta-D-glucopyranosylamine
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 Oryctolagus cuniculus
N-[1-(naphthalen-1-yl)-1H-1,2,3-triazole-4-carbonyl]-beta-D-glucopyranosylamine
-
 Oryctolagus cuniculus
N-[3-(naphthalen-1-yl)-1,2-oxazole-5-carbonyl]-beta-D-glucopyranosylamine
-
 Oryctolagus cuniculus

Organism

Organism UniProt Comment Textmining
Oryctolagus cuniculus P00489
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Source Tissue

Source Tissue Comment Organism Textmining
skeletal muscle
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 Oryctolagus cuniculus
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Synonyms

Synonyms Comment Organism
glycogen phosphorylase b
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 Oryctolagus cuniculus
GPb
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 Oryctolagus cuniculus