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Literature summary for 2.3.3.8 extracted from

  • Rider, C.C.; Wilson, A.P.
    Inhibition of liver ATP citrate lyase in the presence of L-glutamate (1985), Biochem. Soc. Trans., 13, 152-153.
No PubMed abstract available
Search for more literature for 2.3.3.8

Inhibitors

Inhibitors Comment Organism Structure
Glu 10 mM, inhibition is unlikely to be due to any direct interaction of L-Glu and ATP citrate lyase Rattus norvegicus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + citrate + CoA Rattus norvegicus the enzyme is engaged in the transport of acetyl groups from mitochondria to cytosol. On the metabolic pathway from carbohydrate to lipid it is the first enzyme which is exclusively biosynthetic ADP + phosphate + acetyl-CoA + oxaloacetate
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 ?

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
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-
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Source Tissue

Source Tissue Comment Organism Textmining
liver
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 Rattus norvegicus
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + citrate + CoA
-
 Rattus norvegicus ADP + phosphate + acetyl-CoA + oxaloacetate
-
 ?
ATP + citrate + CoA the enzyme is engaged in the transport of acetyl groups from mitochondria to cytosol. On the metabolic pathway from carbohydrate to lipid it is the first enzyme which is exclusively biosynthetic Rattus norvegicus ADP + phosphate + acetyl-CoA + oxaloacetate
-
 ?