BRENDA - Enzyme Database
show all sequences of 2.3.3.3

re-Citrate synthase reaction

Gottschalk, G.; Dittbrenner, S.; Lenz, H.; Eggerer, H.; Eur. J. Biochem. 26, 455-461 (1972)

Data extracted from this reference:

KM Value [mM]
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
0.0015
-
(R)-citryl-CoA
-
Clostridium acidi-urici
0.02
-
(R)-malyl-CoA
-
Clostridium acidi-urici
Organism
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
Clostridium acidi-urici
-
-
-
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
(R)-citryl-CoA + H2O
-
488163
Clostridium acidi-urici
citrate + CoA
-
488163
Clostridium acidi-urici
r
(R)-malyl-CoA + H2O
-
488163
Clostridium acidi-urici
(R)-malate + CoA
-
488163
Clostridium acidi-urici
r
acetyl-CoA + H2O + oxaloacetate
enzyme has acetyl-CoA enolase activity that is induced by 2-oxoglutarate and Co2+
488163
Clostridium acidi-urici
citrate + CoA
-
488163
Clostridium acidi-urici
r
pH Optimum
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
8
-
-
Clostridium acidi-urici
KM Value [mM] (protein specific)
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
0.0015
-
(R)-citryl-CoA
-
Clostridium acidi-urici
0.02
-
(R)-malyl-CoA
-
Clostridium acidi-urici
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
(R)-citryl-CoA + H2O
-
488163
Clostridium acidi-urici
citrate + CoA
-
488163
Clostridium acidi-urici
r
(R)-malyl-CoA + H2O
-
488163
Clostridium acidi-urici
(R)-malate + CoA
-
488163
Clostridium acidi-urici
r
acetyl-CoA + H2O + oxaloacetate
enzyme has acetyl-CoA enolase activity that is induced by 2-oxoglutarate and Co2+
488163
Clostridium acidi-urici
citrate + CoA
-
488163
Clostridium acidi-urici
r
pH Optimum (protein specific)
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
8
-
-
Clostridium acidi-urici
Other publictions for EC 2.3.3.3
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Temperature Optimum [°C]
Temperature Range [°C]
Temperature Stability [°C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [°C] (protein specific)
Temperature Range [°C] (protein specific)
Temperature Stability [°C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
735509
Kim
Two pathways for glutamate bio ...
Syntrophus aciditrophicus
Appl. Environ. Microbiol.
81
8434-8444
2015
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-
-
-
-
-
-
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1
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5
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1
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1
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1
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-
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-
-
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1
1
-
-
-
736357
Kim
Identification and characteriz ...
Syntrophus aciditrophicus, Syntrophus aciditrophicus ATCC 700169
J. Bacteriol.
195
1689-1696
2013
-
-
1
-
-
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7
2
-
5
4
2
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5
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-
1
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1
2
1
4
1
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1
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1
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7
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2
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5
4
2
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1
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1
2
1
4
1
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1
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719729
Marco-Urrea
Identification and characteriz ...
Dehalococcoides sp., Dehalococcoides sp. CBDB1
J. Bacteriol.
193
5171-5178
2011
1
-
1
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4
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1
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4
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1
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4
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1
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1
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4
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1
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1
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4
-
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674333
Li
Re-citrate synthase from Clost ...
Clostridium kluyveri, Desulfovibrio desulfuricans, Desulfovibrio vulgaris
J. Bacteriol.
189
4299-4304
2007
-
-
1
-
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-
3
2
-
-
2
-
-
5
-
-
1
-
1
-
1
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1
1
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1
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3
-
2
-
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2
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1
1
-
1
-
1
1
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-
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-
-
-
-
-
-
-
-
-
-
-
488163
Gottschalk
re-Citrate synthase reaction ...
Clostridium acidi-urici
Eur. J. Biochem.
26
455-461
1972
-
-
-
-
-
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-
2
-
-
-
-
-
1
-
-
-
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-
-
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3
-
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1
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2
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3
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1
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-
-
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-
488162
Wunderwald
Stereochemistry of the re-citr ...
Clostridium acidi-urici
Eur. J. Biochem.
24
216-221
1971
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1
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1
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1
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488158
Goschalk
-
Properties of (R)-citrate synt ...
Clostridium acidi-urici
Hoppe-Seyler's Z. Physiol. chem.
351
1183-1190
1970
1
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8
2
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2
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1
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1
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1
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1
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1
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8
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2
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2
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1
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1
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1
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488157
Gottschalk
Partial purification and some ...
Clostridium acidi-urici
Eur. J. Biochem.
7
301-106
1969
3
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1
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2
1
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1
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1
1
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1
1
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3
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1
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1
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1
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1
1
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-
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1
1
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-
-
-
-
-
-
-
488159
Dittbrenner
The stereospecificity of the ( ...
Clostridium acidi-urici, Clostridium kluyveri
Biochem. Biophys. Res. Commun.
36
802-808
1969
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2
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2
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1
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2
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2
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1
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2
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-
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488160
Stern
Failure of ethylenediaminetetr ...
Clostridium cylindrosporum, Clostridium kluyveri
FEBS Lett.
4
72-74
1969
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2
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2
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2
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2
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2
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2
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2
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488161
O'Brien
Reversal of the stereospecific ...
Clostridium kluyveri
Biochem. Biophys. Res. Commun.
34
271-276
1969
-
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1
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1
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1
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1
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1
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