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Literature summary for 2.3.3.16 extracted from

  • Ruprich-Robert, G.; Zickler, D.; Berteaux-Lecellier, V.; Velot, C.; Picard, M.
    Lack of mitochondrial citrate synthase discloses a new meiotic checkpoint in a strict aerobe (2002), EMBO J., 21, 6440-6451.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.3.3.16

Cloned(Commentary)

Cloned (Comment) Organism
cloning and sequencing Podospora anserina

Protein Variants

Protein Variants Comment Organism
H309G site-directed mutagenesis, mutant allelic strain, altered developmental phenotype Podospora anserina
additional information deletion mutants, altered developmental phenotypes, complete deletion reveals that the enzyme is more important for completion of meiosis than for catalytic activity Podospora anserina

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrion mitochondrial isozyme Saccharomyces cerevisiae 5739
-
mitochondrion mitochondrial isozyme Podospora anserina 5739
-
peroxisome peroxisomal isozyme Saccharomyces cerevisiae 5777
-

Organism

Organism UniProt Comment Textmining
Podospora anserina Q9HFI1 filamentous fungus
-
Podospora anserina Q9HFI1 recessive gene cit1, mitochondrial isozyme
-
Saccharomyces cerevisiae
-
 wild-type strains and citrate synthase deficient strain
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Saccharomyces cerevisiae
-
 peroxisomal isozyme CS II and mitochondrial isozyme CS I
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
acetyl-CoA + oxaloacetate + H2O
-
 Saccharomyces cerevisiae citrate + CoA
-
 ?
acetyl-CoA + oxaloacetate + H2O
-
 Podospora anserina citrate + CoA
-
 ?