Literature summary for 2.3.3.14 extracted from

Demain, A.L.; Masurekar, P.S.
Lysine inhibition of in vivo homocitrate biosynthesis in Penicillium chrysogenum (1974), J. Gen. Microbiol., 82, 143-151.

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Inhibitors

Inhibitors	Comment	Organism	Structure
L-Lys	0.3 mM, 50% inhibition	Penicillium chrysogenum

Organism

Organism	UniProt	Comment	Textmining
Penicillium chrysogenum	-	Wis. 54-1255	-
Penicillium chrysogenum Wis. 54-1255	-	Wis. 54-1255	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
mycelium	-	Penicillium chrysogenum	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
acetyl-CoA + H2O + 2-oxoglutarate	-	Penicillium chrysogenum	2-hydroxybutane-1,2,4-tricarboxylate + CoA	-	?
acetyl-CoA + H2O + 2-oxoglutarate	-	Penicillium chrysogenum Wis. 54-1255	2-hydroxybutane-1,2,4-tricarboxylate + CoA	-	?

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Release 2023.1 (January 2023)