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Literature summary for 2.3.3.10 extracted from

  • Bode, H.B.; Ring, M.W.; Schwaer, G.; Kroppenstedt, R.M.; Kaiser, D.; Mueller, R.
    3-Hydroxy-3-methylglutaryl-coenzyme A (CoA) synthase is involved in biosynthesis of isovaleryl-CoA in the myxobacterium Myxococcus xanthus during fruiting body formation (2006), J. Bacteriol., 188, 6524-6528.
    View publication on PubMedView publication on EuropePMC

Protein Variants

Protein Variants Comment Organism
additional information construction of a double mutant by deletion of genes involved in leucine degradation and disruption of hydroxymethylglutaryl-Coa synthase gene. For the mutant, a dramatic decrease is observed of isovaleryl-CoA derived iso-odd fatty acids Myxococcus xanthus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Myxococcus xanthus hydroxymethylglutaryl-CoA synthase is involved in an alternative pathway for isovaleryl-coA synthesis ?
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?

Organism

Organism UniProt Comment Textmining
Myxococcus xanthus
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hydroxymethylglutaryl-CoA synthase is transcriptionally regulated by isovalerate
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information hydroxymethylglutaryl-CoA synthase is involved in an alternative pathway for isovaleryl-coA synthesis Myxococcus xanthus ?
-
?