Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 2.3.3.10 extracted from

  • Casals, N.; Buesa, C.; Marrero, P.F.; Belles, X.; Hegardt, F.G.
    3-Hydroxy-3-methylglutaryl coenzyme A synthase-1 of Blattella germanica has structural and functional features of an active retrogene (2001), Insect Biochem. Mol. Biol., 31, 425-433.
    View publication on PubMed
Search for more literature for 2.3.3.10

Cloned(Commentary)

Cloned (Comment) Organism
intronless gene, encodes for an active enzyme able to complement eukaryotic Mev-1 cells Blattella germanica

Localization

Localization Comment Organism GeneOntology No. Textmining

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
acetyl-CoA + acetoacetyl-CoA + H2O Blattella germanica mevalonate pathway (S)-3-hydroxy-3-methylglutaryl-CoA + CoA
-
 ?

Organism

Organism UniProt Comment Textmining
Blattella germanica
-
 cockroach
-

Source Tissue

Source Tissue Comment Organism Textmining
embryo
-
 Blattella germanica
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
acetyl-CoA + acetoacetyl-CoA + H2O
-
 Blattella germanica (S)-3-hydroxy-3-methylglutaryl-CoA + CoA
-
 ?
acetyl-CoA + acetoacetyl-CoA + H2O mevalonate pathway Blattella germanica (S)-3-hydroxy-3-methylglutaryl-CoA + CoA
-
 ?
additional information first organism known to have 2 functional cytosolic HMG-CoA synthases Blattella germanica ?
-
 ?