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Literature summary for 2.3.3.10 extracted from

  • Montamat, F.; Guilloton, M.; Karst, F.; Delrot, S.
    Isolation and characterization of a cDNA encoding Arabidopsis thaliana 3-hydroxy-3-methylglutaryl-coenzyme A synthase (1995), Gene, 167, 197-201.
    View publication on PubMed
Search for more literature for 2.3.3.10

Cloned(Commentary)

Cloned (Comment) Organism
cDNA cloned by complementation of a bap1 mutation and expressed in Saccharomyces cerevisiae Arabidopsis thaliana

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane
-
 Arabidopsis thaliana 16020
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
51040
-
 predicted from cDNA sequence Arabidopsis thaliana
55500
-
 SDS-PAGE Arabidopsis thaliana
57250
-
 deduced amino acid sequence Cricetulus griseus
57290
-
 deduced amino acid sequence Homo sapiens
57370
-
 deduced amino acid sequence Rattus norvegicus
57490
-
 deduced amino acid sequence Gallus gallus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
acetyl-CoA + acetoacetyl-CoA + H2O Gallus gallus
-
 (S)-3-hydroxy-3-methylglutaryl-CoA + CoA
-
 ?
acetyl-CoA + acetoacetyl-CoA + H2O Cricetulus griseus
-
 (S)-3-hydroxy-3-methylglutaryl-CoA + CoA
-
 ?
acetyl-CoA + acetoacetyl-CoA + H2O Homo sapiens
-
 (S)-3-hydroxy-3-methylglutaryl-CoA + CoA
-
 ?
acetyl-CoA + acetoacetyl-CoA + H2O Rattus norvegicus
-
 (S)-3-hydroxy-3-methylglutaryl-CoA + CoA
-
 ?
acetyl-CoA + acetoacetyl-CoA + H2O Raphanus sativus
-
 (S)-3-hydroxy-3-methylglutaryl-CoA + CoA
-
 ?
acetyl-CoA + acetoacetyl-CoA + H2O Catharanthus roseus
-
 (S)-3-hydroxy-3-methylglutaryl-CoA + CoA
-
 ?
acetyl-CoA + acetoacetyl-CoA + H2O Arabidopsis thaliana key role in synthesis of various sterols and isoprenoids (S)-3-hydroxy-3-methylglutaryl-CoA + CoA
-
 ?

Organism

Organism UniProt Comment Textmining
Arabidopsis thaliana
-
-
-
Catharanthus roseus
-
-
-
Cricetulus griseus
-
 chinese hamster
-
Gallus gallus
-
 chicken
-
Homo sapiens
-
 human
-
Raphanus sativus
-
 radish
-
Rattus norvegicus
-
 rat
-

Purification (Commentary)

Purification (Comment) Organism
-
 Arabidopsis thaliana

Source Tissue

Source Tissue Comment Organism Textmining
fibroblast
-
 Homo sapiens
-
liver
-
 Gallus gallus
-
liver
-
 Rattus norvegicus
-
ovary
-
 Cricetulus griseus
-
seedling
-
 Raphanus sativus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
acetyl-CoA + acetoacetyl-CoA + H2O
-
 Gallus gallus (S)-3-hydroxy-3-methylglutaryl-CoA + CoA
-
 ?
acetyl-CoA + acetoacetyl-CoA + H2O
-
 Cricetulus griseus (S)-3-hydroxy-3-methylglutaryl-CoA + CoA
-
 ?
acetyl-CoA + acetoacetyl-CoA + H2O
-
 Homo sapiens (S)-3-hydroxy-3-methylglutaryl-CoA + CoA
-
 ?
acetyl-CoA + acetoacetyl-CoA + H2O
-
 Rattus norvegicus (S)-3-hydroxy-3-methylglutaryl-CoA + CoA
-
 ?
acetyl-CoA + acetoacetyl-CoA + H2O
-
 Arabidopsis thaliana (S)-3-hydroxy-3-methylglutaryl-CoA + CoA
-
 ?
acetyl-CoA + acetoacetyl-CoA + H2O
-
 Raphanus sativus (S)-3-hydroxy-3-methylglutaryl-CoA + CoA
-
 ?
acetyl-CoA + acetoacetyl-CoA + H2O
-
 Catharanthus roseus (S)-3-hydroxy-3-methylglutaryl-CoA + CoA
-
 ?
acetyl-CoA + acetoacetyl-CoA + H2O key role in synthesis of various sterols and isoprenoids Arabidopsis thaliana (S)-3-hydroxy-3-methylglutaryl-CoA + CoA
-
 ?