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Literature summary for 2.3.2.5 extracted from

  • Schilling, S.; Zeitschel, U.; Hoffmann, T.; Heiser, U.; Francke, M.; Kehlen, A.; Holzer, M.; Hutter-Paier, B.; Prokesch, M.; Windisch, M.; Jagla, W.; Schlenzig, D.; Lindner, C.; Rudolph, T.; Reuter, G.; Cynis, H.; Montag, D.; Demuth, H.U.; Rossner, S.
    Glutaminyl cyclase inhibition attenuates pyroglutamate Abeta and Alzheimers disease-like pathology (2008), Nat. Med., 14, 1106-1111.
    View publication on PubMed

Application

Application Comment Organism
medicine inhibition of glutaminyl cyclase offers a new therapeutic option for the treatment of Alzheimer’s disease and provides implications for other amyloidoses, such as familial Danish dementia Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
brain
-
Homo sapiens
-

Synonyms

Synonyms Comment Organism
glutaminyl cyclase
-
Homo sapiens