Inhibitors | Comment | Organism | Structure |
---|---|---|---|
1-(3,4-dimethoxyphenyl)-3-[3-(1H-imidazol-1-yl)propyl]thiourea | i.e. P150/03, complete inhibition at 0.01 mM | Homo sapiens | |
1-(3,4-dimethoxyphenyl)-3-[3-(1H-imidazol-1-yl)propyl]thiourea | i.e. P150/03, complete inhibition at 0.01 mM | Mus musculus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Mus musculus | enzyme is important during cellular maturation of L-pyroglutamyl-containing peptides | ? | - |
? | |
additional information | Homo sapiens | enzyme is important during cellular maturation of L-pyroglutamyl-containing peptides | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Mus musculus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
beta-TC3 cell | - |
Mus musculus | - |
HEK-293 cell | - |
Homo sapiens | - |
HeLa cell | - |
Homo sapiens | - |
L-363 cell | plasma cell leukemia cell line | Homo sapiens | - |
L-929 cell | - |
Mus musculus | - |
RAW-264.7 cell | - |
Mus musculus | - |
U-343 cell | glioma cell | Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-Gln(3)-amyloid-beta peptide 3-42 | - |
Mus musculus | L-pyroglutamyl(3)-amyloid-beta peptide 3-42 + NH3 | - |
? | |
L-Gln(3)-amyloid-beta peptide 3-42 | - |
Homo sapiens | L-pyroglutamyl(3)-amyloid-beta peptide 3-42 + NH3 | - |
? | |
L-Gln-2-naphthylamide | reaction in cell supernatant is exclusively enzyme-catalyzed | Mus musculus | L-pyroglutamyl-2-naphthylamide + NH3 | - |
? | |
L-Gln-2-naphthylamide | reaction in cell supernatant is exclusively enzyme-catalyzed | Homo sapiens | L-pyroglutamyl-2-naphthylamide + NH3 | - |
? | |
L-Glu(3)-amyloid-beta peptide 3-42 | - |
Mus musculus | L-pyroglutamyl(3)-amyloid-beta peptide 3-42 + H2O | - |
? | |
L-Glu(3)-amyloid-beta peptide 3-42 | - |
Homo sapiens | L-pyroglutamyl(3)-amyloid-beta peptide 3-42 + H2O | - |
? | |
additional information | enzyme is important during cellular maturation of L-pyroglutamyl-containing peptides | Mus musculus | ? | - |
? | |
additional information | enzyme is important during cellular maturation of L-pyroglutamyl-containing peptides | Homo sapiens | ? | - |
? |