Cloned (Comment) | Organism |
---|---|
expression in COS-7 cell and 293-T cell | Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
nucleus | - |
Homo sapiens | 5634 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | Q8IYM9 | isoform TRIM22 | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
[TRIM22-ubiquitin-carrier protein UbcH5B]-S-ubiquitinyl-L-cysteine + [TRIM22]-L-lysine | - |
Homo sapiens | [TRIM22-ubiquitin-carrier protein UbcH5B]-L-cysteine + [TRIM22]-N6-ubiquitinyl-L-lysine | isoform undergoes self-ubiquitylation in vitro in combination with the E2 enzyme UbcH5B, the ubiquitylation is dependent on its RING finger domain. TRIM22 is conjugated with poly-ubiquitin chains and stabilized by proteasome inhibitor in 293T cells | ? |
Synonyms | Comment | Organism |
---|---|---|
TRIM22 | - |
Homo sapiens |