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Literature summary for 2.3.2.15 extracted from

  • Li, H.; Cong, Y.; Lin, J.; Chang, Y.
    Enhanced tolerance and accumulation of heavy metal ions by engineered Escherichia coli expressing Pyrus calleryana phytochelatin synthase (2015), J. Basic Microbiol., 55, 398-405.
    View publication on PubMed
Search for more literature for 2.3.2.15

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Escherichia coli Rosetta (DE3) cells Pyrus calleryana

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
glutathione + [Glu(-Cys)]n-Gly Pyrus calleryana
-
 Gly + [Glu(-Cys)]n+1-Gly
-
 ?

Organism

Organism UniProt Comment Textmining
Pyrus calleryana
-
 bean pear
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
glutathione + [Glu(-Cys)]n-Gly
-
 Pyrus calleryana Gly + [Glu(-Cys)]n+1-Gly
-
 ?

Synonyms

Synonyms Comment Organism
glutathione gamma-glutamylcysteinyltransferase
-
 Pyrus calleryana
PCS1
-
 Pyrus calleryana
phytochelatin synthase
-
 Pyrus calleryana

Expression

Organism Comment Expression
Pyrus calleryana enzyme expression is induced after cadmium and copper treatments up

General Information

General Information Comment Organism
physiological function the enzyme has a major role in the detoxification of heavy metals. Escherichia coli with overexpressed phytochelatin synthase 1 has enhanced tolerance to cadmium, copper, sodium, and mercury Pyrus calleryana