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Literature summary for 2.3.2.12 extracted from

  • Gupta, R.; Lavollay, M.; Mainardi, J.L.; Arthur, M.; Bishai, W.R.; Lamichhane, G.
    The Mycobacterium tuberculosis protein LdtMt2 is a nonclassical transpeptidase required for virulence and resistance to amoxicillin (2010), Nat. Med., 16, 466-469.
    View publication on PubMedView publication on EuropePMC

Organism

Organism UniProt Comment Textmining

General Information

General Information Comment Organism
malfunction loss of L,D-transpeptidase gene MT2594 does not alter susceptibility to isoniazid and D-cycloserine, but is associated with increased susceptibility to amoxicillin in the presence of clavulanic acid Mycobacterium tuberculosis
physiological function the LdtMt2 protein is required for virulence and resistance to amoxicillin Mycobacterium tuberculosis