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Literature summary for 2.3.1.B43 extracted from
- Mitochondrial SIRT5 is present in follicular cells and is altered by reduced ovarian reserve and advanced maternal age (2014), Reprod. Fertil. Dev., 26, 1072-1083.
Application
| Application | Comment | Organism |
|---|---|---|
| medicine | SIRT5 is involved in influencing oocyte quality and in-vitro-fertilisation outcomes | Homo sapiens |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| mitochondrion | - |
Homo sapiens | 5739 | - |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | Q9NXA8 | - |
- |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| SIRT5 | - |
Homo sapiens |
| sirtuin 5 | - |
Homo sapiens |
Expression
| Organism | Comment | Expression |
|---|---|---|
| Homo sapiens | women with reduced ovarian reserve or advanced maternal age have decreased SIRT5 mRNA, protein and desuccinylation activity in granulosa and cumulus cells | down |
General Information
| General Information | Comment | Organism |
|---|---|---|
| physiological function | SIRT5 is involved in influencing oocyte quality and in-vitro-fertilisation outcomes | Homo sapiens |
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Release 2023.1 (January 2023)
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