Literature summary for 2.3.1.B43 extracted from

Schlicker, C.; Gertz, M.; Papatheodorou, P.; Kachholz, B.; Becker, C.F.; Steegborn, C.
Substrates and regulation mechanisms for the human mitochondrial sirtuins Sirt3 and Sirt5 (2008), J. Mol. Biol., 382, 790-801.

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Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
mitochondrion	Sirt5 can be translocated into the mitochondrial intermembrane space, but also into the matrix	Homo sapiens	5739	-

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	Q9NXA8	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
additional information	Sirt5 does not deacetylate glutamate dehydrogenase or isocitrate dehydrogenase 2	Homo sapiens	?	-	?
NAD+ + [cytochrome c]-N6-acetyl-L-lysine	-	Homo sapiens	nicotinamide + [cytochrome c]-L-lysine + 2'-O-acetyl-ADP-ribose	-	?

Synonyms

Synonyms	Comment	Organism
SIRT5	-	Homo sapiens

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Release 2023.1 (January 2023)