Literature summary for 2.3.1.B41 extracted from

Pan, P.W.; Feldman, J.L.; Devries, M.K.; Dong, A.; Edwards, A.M.; Denu, J.M.
Structure and biochemical functions of SIRT6 (2011), J. Biol. Chem., 286, 14575-14587.

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Cloned(Commentary)

Cloned (Comment)	Organism
-	Homo sapiens

Crystallization (Commentary)

Crystallization (Comment)	Organism
hanging drop vapor diffusion at 20°C. Crystal structures in complex with ADP-ribose and the non-hydrolyzable analog of O-acetyl-ADP-ribose, 2'-N-acetyl-ADP-ribose	Homo sapiens

Protein Variants

Protein Variants	Comment	Organism
H131Y	the mutant enzyme can still bind NAD+ but has a decreased ability to bind ADP-ribose	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	Q8N6T7	-	-

Purification (Commentary)

Purification (Comment)	Organism
-	Homo sapiens

Synonyms

Synonyms	Comment	Organism
SIRT6	-	Homo sapiens

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Release 2023.1 (January 2023)