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Literature summary for 2.3.1.B41 extracted from

  • Liu, R.; Liu, H.; Ha, Y.; Tilton, R.G.; Zhang, W.
    Oxidative stress induces endothelial cell senescence via downregulation of Sirt6 (2014), Biomed Res. Int., 2014, 902842.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.3.1.B41

Organism

Organism UniProt Comment Textmining
Homo sapiens Q8N6T7
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-

Source Tissue

Source Tissue Comment Organism Textmining
HUVEC cell
-
 Homo sapiens
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Synonyms

Synonyms Comment Organism
SIRT6
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 Homo sapiens
sirtuin 6
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 Homo sapiens

Expression

Organism Comment Expression
Homo sapiens H2O2 treatment significantly reduces Sirt6 protein. Stress-induced downregulation of Sirt6 is likely involved in the pathogenesis of diabetic retinopathy down

General Information

General Information Comment Organism
physiological function Sirt6 is a critical regulator of endothelial senescence Homo sapiens