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Literature summary for 2.3.1.99 extracted from

  • Sander, M.; Petersen, M.
    Distinct substrate specificities and unusual substrate flexibilities of two hydroxycinnamoyltransferases, rosmarinic acid synthase and hydroxycinnamoyl-CoA:shikimate hydroxycinnamoyl-transferase, from Coleus blumei Benth. (2011), Planta, 233, 1157-1171.
    View publication on PubMed
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Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
4-coumaroyl-CoA + quinate Coleus scutellarioides
-
 CoA + 4-coumaroylquinate
-
 ?

Organism

Organism UniProt Comment Textmining
Coleus scutellarioides
-
 syn. Solenostemon scutellarioides
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4-coumaroyl-CoA + quinate
-
 Coleus scutellarioides CoA + 4-coumaroylquinate
-
 ?

Synonyms

Synonyms Comment Organism
HQT
-
 Coleus scutellarioides
hydroxycinnamoyl-CoA:quinate hydroxycinnamoyltransferase
-
 Coleus scutellarioides

General Information

General Information Comment Organism
evolution the enzyme belongs to the superfamily of BAHD acyltransferases. The conserved sequence motifs HxxxDG and DFGWG are surrounded by differing amino acid environments which show typical features for hydroxycinnamoyl-CoA:hydroxyphenyllactic acid hydroxycinnamoyltransferase, RAS, and hydroxycinnamoyl-CoA:shikimic acid hydroxycinnamoyltransferase/hydroxycinnamoyl-CoA:quinate hydroxycinnamoyltransferase, HST/HQT Coleus scutellarioides
metabolism quinate is used as acceptor molecule by a HQT and 4-coumaroylquinate is formed, which is hydroxylated by a member of the CYP98A family to chlorogenic acid Coleus scutellarioides