Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
myristoyl-CoA + glycylpeptide | Saccharomyces cerevisiae | enzyme is essential for vegetative growth | N-myristoylglycylpeptide + CoA | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Saccharomyces cerevisiae | - |
recombinant Nmt1p from Escherichia coli | - |
Reaction | Comment | Organism | Reaction ID |
---|---|---|---|
tetradecanoyl-CoA + an N-terminal-glycyl-[protein] = CoA + an N-terminal-N-tetradecanoylglycyl-[protein] | ordered bi bi mechanism | Saccharomyces cerevisiae | |
tetradecanoyl-CoA + an N-terminal-glycyl-[protein] = CoA + an N-terminal-N-tetradecanoylglycyl-[protein] | peptide binding site | Saccharomyces cerevisiae |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
myristoyl-CoA + glycylpeptide | substrate specificity | Saccharomyces cerevisiae | N-myristoylglycylpeptide + CoA | - |
? | |
myristoyl-CoA + glycylpeptide | myristoyl-CoA can be replaced by CoA-derivatives of hydroxytetradecanoic acids, azidoaromatic analogues of myristic acid, omega-nitrocarboxylic acids, halogen- and haloaromatic analogues of myristic acid and, with low activity, by dicarboxylic fatty acids | Saccharomyces cerevisiae | N-myristoylglycylpeptide + CoA | - |
? | |
myristoyl-CoA + glycylpeptide | stereochemical requirements | Saccharomyces cerevisiae | N-myristoylglycylpeptide + CoA | - |
? | |
myristoyl-CoA + glycylpeptide | specific for Gly at N-terminus | Saccharomyces cerevisiae | N-myristoylglycylpeptide + CoA | - |
? | |
myristoyl-CoA + glycylpeptide | enzyme is essential for vegetative growth | Saccharomyces cerevisiae | N-myristoylglycylpeptide + CoA | - |
? | |
myristoyl-CoA + Pr55gag-precursor-derived octapeptide | peptide substrate is derived from human immunodeficiency virus | Saccharomyces cerevisiae | N-myristoylated Pr55gag-precursor-derived peptide + CoA | - |
? |
Synonyms | Comment | Organism |
---|---|---|
Nmt1p | - |
Saccharomyces cerevisiae |