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Literature summary for 2.3.1.94 extracted from
- 6-Deoxyerythronolide B production through chromosomal localization of the deoxyerythronolide B synthase genes in E. coli (2008), Metab. Eng., 10, 33-38.
Application
| Application | Comment | Organism |
|---|---|---|
| biotechnology | a new Escherichia coli stain, YW9, is created, featuring a plasmid-free heterologous pathway for the production of the polyketide product 6-deoxyerythronolide B | Saccharopolyspora erythraea |
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| the three DEBS genes are sequentially integrated into the Escherichia coli BAP1 chromosome | Saccharopolyspora erythraea |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| propanoyl-CoA + 6 (2S)-methylmalonyl-CoA + 6 NADPH + 6 H+ | Saccharopolyspora erythraea | - |
6-deoxyerythronolide B + 7 CoA + 6 CO2 + H2O + 6 NADP+ | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Saccharopolyspora erythraea | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| propanoyl-CoA + 6 (2S)-methylmalonyl-CoA + 6 NADPH + 6 H+ | - |
Saccharopolyspora erythraea | 6-deoxyerythronolide B + 7 CoA + 6 CO2 + H2O + 6 NADP+ | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| DEBS | - |
Saccharopolyspora erythraea |
| deoxyerythronolide B synthase | - |
Saccharopolyspora erythraea |
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