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Literature summary for 2.3.1.71 extracted from
- New insights into the catalytic mechanism of human glycine N-acyltransferase (2017), J. Biochem. Mol. Toxicol., 31, e21963 .
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expressed in Escherichia coli | Homo sapiens |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.049 | - |
benzoyl-CoA | purified recombinant S156 haplotype, apparent value, random bi-bi (sequential) mechanism, at pH 8.0, temperature not specified in the publication | Homo sapiens |  |
| 0.053 | - |
benzoyl-CoA | purified recombinant S156 haplotype, apparent value, ping-pong bi-bi (non-sequential) mechanism, at pH 8.0, temperature not specified in the publication | Homo sapiens | |
| 0.06 | - |
benzoyl-CoA | purified recombinant S156 haplotype, apparent value, ordered bi-bi (sequential) mechanism, at pH 8.0, temperature not specified in the publication | Homo sapiens | |
| 5 | - |
glycine | purified recombinant S156 haplotype, apparent value, ordered bi-bi (sequential) mechanism, at pH 8.0, temperature not specified in the publication | Homo sapiens | |
| 20 | - |
glycine | purified recombinant S156 haplotype, apparent value, random bi-bi (sequential) mechanism, at pH 8.0, temperature not specified in the publication | Homo sapiens | |
| 21 | - |
glycine | purified recombinant S156 haplotype, apparent value, ping-pong bi-bi (non-sequential) mechanism, at pH 8.0, temperature not specified in the publication | Homo sapiens | |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| benzoyl-CoA + glycine | Homo sapiens | - |
CoA + hippurate | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| nickel-affinity column chromatography | Homo sapiens |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| liver | - |
Homo sapiens | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| benzoyl-CoA + glycine | - |
Homo sapiens | CoA + hippurate | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| GlyAT | - |
Homo sapiens |
| glycine N-acyltransferase | - |
Homo sapiens |
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Release 2023.1 (January 2023)
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