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Literature summary for 2.3.1.7 extracted from

  • Hynes, M.J.; Murray, S.L.; Andrianopoulos, A.; Davis, M.A.
    Role of carnitine acetyltransferases in acetyl coenzyme A metabolism in Aspergillus nidulans (2011), Eukaryot. Cell, 10, 547-555.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.3.1.7

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrion sequence contains a N-terminal mitochondrial targeting sequence and a C-terminal peroxisomal targeting sequence and protein is localized to both peroxisomes and mitochondria Aspergillus nidulans 5739
-
peroxisome sequence contains a N-terminal mitochondrial targeting sequence and a C-terminal peroxisomal targeting sequence and protein is localized to both peroxisomes and mitochondria Aspergillus nidulans 5777
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
68500
-
 x * 68500, calculated Aspergillus nidulans

Organism

Organism UniProt Comment Textmining
Aspergillus nidulans
-
-
-

Posttranslational Modification

Posttranslational Modification Comment Organism
proteolytic modification sequence contains a N-terminal mitochondrial targeting sequence and a C-terminal peroxisomal targeting sequence and protein is localized to both peroxisomes and mitochondria Aspergillus nidulans

Subunits

Subunits Comment Organism
? x * 68500, calculated Aspergillus nidulans

Synonyms

Synonyms Comment Organism
acuJ
-
 Aspergillus nidulans

General Information

General Information Comment Organism
physiological function protein is essential for growth on fatty acids as well as acetate. Mislocalization of the enzyme to the cytoplasm does not result in loss of growth on acetate but prevents growth on fatty acids. The mitochondrial enzyme is essential for the transfer of acetyl units to mitochondria, peroxisomal localization is required only for transfer from peroxisomes to mitochondria. Peroxisomal enzyme is not required for the import of acetyl-CoA into peroxisomes for conversion to malate by malate synthase, and export of acetyl-CoA from peroxisomes to the cytoplasm is independent of FacC when malate synthase is mislocalized to the cytoplasm Aspergillus nidulans