Cloned (Comment) | Organism |
---|---|
- |
Mus musculus |
- |
Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
microsome | microsomal protein with three putative membrane-spanning domains | Mus musculus | - |
- |
microsome | microsomal protein with three putative membrane-spanning domains | Homo sapiens | - |
- |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Mus musculus | enzyme is induced by bacterial endotoxin. The enzyme catalyzes not only biosynthesis of PAF from lyso-PAF but also incorporation of arachidonoyl-CoA to produce PAF precursor membrane glycerophospholipids (lysophosphatidylcholine acyltransferase activity). Under resting conditions, the enzyme prefers arachidonoyl-CoA and contributes to membrane biogenesis. Upon acute inflammatory stimulation with lipopolysaccharide, the activated enzyme utilizes acetyl-CoA more efficiently and produces PAF | ? | - |
? | |
additional information | Homo sapiens | enzyme is induced by bacterial endotoxin. The enzyme catalyzes not only biosynthesis of PAF from lyso-PAF but also incorporation of arachidonoyl-CoA to produce PAF precursor membrane glycerophospholipids (lysophosphatidylcholine acyltransferase activity). Under resting conditions, the enzyme prefers arachidonoyl-CoA and contributes to membrane biogenesis. Upon acute inflammatory stimulation with lipopolysaccharide, the activated enzyme utilizes acetyl-CoA more efficiently and produces PAF | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | Q7L5N7 | - |
- |
Mus musculus | Q8BYI6 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
acetyl-CoA + lyso-platelet-activating factor | - |
Mus musculus | platelet-activating factor + CoA | - |
? | |
acetyl-CoA + lyso-platelet-activating factor | - |
Homo sapiens | platelet-activating factor + CoA | - |
? | |
additional information | enzyme is induced by bacterial endotoxin. The enzyme catalyzes not only biosynthesis of PAF from lyso-PAF but also incorporation of arachidonoyl-CoA to produce PAF precursor membrane glycerophospholipids (lysophosphatidylcholine acyltransferase activity). Under resting conditions, the enzyme prefers arachidonoyl-CoA and contributes to membrane biogenesis. Upon acute inflammatory stimulation with lipopolysaccharide, the activated enzyme utilizes acetyl-CoA more efficiently and produces PAF | Mus musculus | ? | - |
? | |
additional information | enzyme is induced by bacterial endotoxin. The enzyme catalyzes not only biosynthesis of PAF from lyso-PAF but also incorporation of arachidonoyl-CoA to produce PAF precursor membrane glycerophospholipids (lysophosphatidylcholine acyltransferase activity). Under resting conditions, the enzyme prefers arachidonoyl-CoA and contributes to membrane biogenesis. Upon acute inflammatory stimulation with lipopolysaccharide, the activated enzyme utilizes acetyl-CoA more efficiently and produces PAF | Homo sapiens | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
acetyl-CoA:lyso-PAF acetyltransferase | - |
Mus musculus |
acetyl-CoA:lyso-PAF acetyltransferase | - |
Homo sapiens |
lpafat1 | - |
Homo sapiens |
lyso-PAF acetyltransferase:LPC acyltransferase 1 | - |
Mus musculus |
lyso-PAF acetyltransferase:LPC acyltransferase 1 | - |
Homo sapiens |
mLysoPAFAT/LPCAT2 | - |
Mus musculus |