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Literature summary for 2.3.1.61 extracted from

  • Hoffelder, M.; Raasch, K.; van Ooyen, J.; Eggeling, L.
    The E2 domain of OdhA of Corynebacterium glutamicum has succinyltransferase activity dependent on lipoyl residues of the acetyltransferase AceF (2010), J. Bacteriol., 192, 5203-5211.
    View publication on PubMedView publication on EuropePMC

Organism

Organism UniProt Comment Textmining
Corynebacterium glutamicum Q8NNJ2
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-

Synonyms

Synonyms Comment Organism
AceF
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Corynebacterium glutamicum

General Information

General Information Comment Organism
physiological function isolated isoform AceF has solely transacetylase activity and no transsuccinylase activity. Oxoglutarate dehydrogenase complex OdhA specifically converts 2-oxoglutarate to succinyl-coenzyme A but fully relies on the lipoyl residues provided by AceF involved in the reactions to convert pyruvate to acetyl-CoA. Presence of isoform AceF is required for both oxoglutarate dehydrogenase and pyruvate dehydrogenase activity Corynebacterium glutamicum