BRENDA - Enzyme Database show
show all sequences of 2.3.1.60

Modifying enzymes related aminoglycoside: analyses of resistant Acinetobacter isolates

Atasoy, A.R.; Ciftci, I.H.; Petek, M.; Int. J. Clin. Exp. Med. 8, 2874-2880 (2015)

Data extracted from this reference:

Cloned(Commentary)
Commentary
Organism
gene aacC1, genotyping
Acinetobacter baumannii
Inhibitors
Inhibitors
Commentary
Organism
Structure
additional information
determination of imipenem, meropenem, and gentamicin resistant clinical isolates
Acinetobacter baumannii
Natural Substrates/ Products (Substrates)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
additional information
Acinetobacter baumannii
determination of imipenem, meropenem, and gentamicin resistant clinical isolates
?
-
-
-
Organism
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
Acinetobacter baumannii
O05286
gene aacC1; diverse clinical isolates, gene aacC1
-
Source Tissue
Source Tissue
Commentary
Organism
Textmining
additional information
analysis of enzyme expression in several clinical isolates, overview
Acinetobacter baumannii
-
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
additional information
determination of imipenem, meropenem, and gentamicin resistant clinical isolates
736260
Acinetobacter baumannii
?
-
-
-
-
Cloned(Commentary) (protein specific)
Commentary
Organism
gene aacC1, genotyping
Acinetobacter baumannii
Inhibitors (protein specific)
Inhibitors
Commentary
Organism
Structure
additional information
determination of imipenem, meropenem, and gentamicin resistant clinical isolates
Acinetobacter baumannii
Natural Substrates/ Products (Substrates) (protein specific)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
additional information
Acinetobacter baumannii
determination of imipenem, meropenem, and gentamicin resistant clinical isolates
?
-
-
-
Source Tissue (protein specific)
Source Tissue
Commentary
Organism
Textmining
additional information
analysis of enzyme expression in several clinical isolates, overview
Acinetobacter baumannii
-
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
additional information
determination of imipenem, meropenem, and gentamicin resistant clinical isolates
736260
Acinetobacter baumannii
?
-
-
-
-
General Information
General Information
Commentary
Organism
additional information
presence of genes encoding the following aminoglycoside-modifying en­zymes: aph (3')-V1, aph (3')-Ia, aac (3)-Ia, aac (3) IIa, aac (6')-Ih, aac (6')-Ib and ant (2')-Ia responsible for resis­tance in 4 different groups of clinical isolates, overview
Acinetobacter baumannii
General Information (protein specific)
General Information
Commentary
Organism
additional information
presence of genes encoding the following aminoglycoside-modifying en­zymes: aph (3')-V1, aph (3')-Ia, aac (3)-Ia, aac (3) IIa, aac (6')-Ih, aac (6')-Ib and ant (2')-Ia responsible for resis­tance in 4 different groups of clinical isolates, overview
Acinetobacter baumannii
Other publictions for EC 2.3.1.60
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Temperature Optimum [°C]
Temperature Range [°C]
Temperature Stability [°C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [°C] (protein specific)
Temperature Range [°C] (protein specific)
Temperature Stability [°C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
736260
Atasoy
Modifying enzymes related amin ...
Acinetobacter baumannii
Int. J. Clin. Exp. Med.
8
2874-2880
2015
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1
1
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706886
Ahmed
Genetic analysis of antimicrob ...
Escherichia coli
Vet. Microbiol.
136
397-402
2009
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1
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637303
Vliegenthart
Identification of three genes ...
Escherichia coli
J. Antimicrob. Chemother.
25
759-765
1990
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637302
Williams
Substrate specificity and stru ...
Escherichia coli, Escherichia coli C600
J. Biol. Chem.
253
5908-5914
1978
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13
1
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7
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10
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10
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21
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637298
Williams
Purification and properties of ...
Escherichia coli, Escherichia coli C600
Biochemistry
15
125-131
1976
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2
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2
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9
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