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Literature summary for 2.3.1.6 extracted from
- Transcriptional activation of human choline acetyltransferase by AP2- and NGF-induced factors (1997), Mol. Brain Res., 49, 165-174.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| NGFI-A | NGF activates transcriptional factors which influence the promotor region of the enzyme | Homo sapiens | |
| NGFI-C | NGF activates transcriptional factors which influence the promotor region of the enzyme | Homo sapiens |
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| two fragments of the hChAT gene are used for functional analysis carrying 944 bp (P1) and 4000 bp (P2) of the 5' flanking region in front of the chloramphenicol acetyltransferase (CAT) reporter gene. They are transfected in NG108-15, SN6 and COS-1 cells | Homo sapiens |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| acetyl-CoA + choline | - |
Homo sapiens | acetylcholine + CoA | - |
? |  |
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