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Literature summary for 2.3.1.58 extracted from
- Biosynthesis of beta-N-oxalyl-L-alpha,beta-diaminopropionic acid, the Lathyrus sativus neurotoxin (1970), Phytochemistry, 9, 1603-1610.
No PubMed abstract available
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| EDTA | slight activation | Lathyrus sativus |  |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| acetone | precipitation with acetone completely inhibits enzyme activity | Lathyrus sativus | |
| ethanol | precipitation with ethanol completely inhibits enzyme activity | Lathyrus sativus | |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.3 | - |
L-2,3-diaminopropionic acid | - |
Lathyrus sativus | |
| 0.45 | - |
oxalyl-CoA | - |
Lathyrus sativus | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Lathyrus sativus | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| 60fold | Lathyrus sativus |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| seedling | - |
Lathyrus sativus | - |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| additional information | - |
- |
Lathyrus sativus |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | succinyl-CoA and acetyl-CoA are not accepted | Lathyrus sativus | ? | - |
? | |
| oxalyl-CoA + 2,4-diaminobutyric acid | about 20% of activity with L-2,3-diaminopropionic acid | Lathyrus sativus | CoA + N4-oxalyl-2,4-diaminobutyric acid | - |
? | |
| oxalyl-CoA + L-2,3-diaminopropionic acid | - |
Lathyrus sativus | CoA + N3-oxalyl-L-2,3-diaminopropionic acid | - |
? | |
| oxalyl-CoA + L-homoserine | about 12% of activity with L-2,3-diaminopropionic acid | Lathyrus sativus | ? | - |
? | |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 37 | - |
assay at | Lathyrus sativus |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 7.4 | 8 | - |
Lathyrus sativus |
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Release 2023.1 (January 2023)
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