Inhibitors | Comment | Organism | Structure |
---|---|---|---|
methacrylate | suicide inhibition mechanism, possibly involving also Arg176 and Arg435, binds to Cys419, modeling, overview | Escherichia coli |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
CoA + pyruvate | Escherichia coli | - |
acetyl-CoA + formate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Escherichia coli | - |
- |
- |
Reaction | Comment | Organism | Reaction ID |
---|---|---|---|
acetyl-CoA + formate = CoA + pyruvate | catalytic mechanism involving residues Gly734, Cys418 and Cys419, transition state, modeling, overview | Escherichia coli |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
CoA + pyruvate | - |
Escherichia coli | acetyl-CoA + formate | - |
? | |
CoA + pyruvate | the reaction involves Cys418 and Cys419 | Escherichia coli | acetyl-CoA + formate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
pyruvate formate lyase | - |
Escherichia coli |