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Literature summary for 2.3.1.54 extracted from

  • Wagner, A.F.V.; Schultz, S.; Bomke, J.; Pils, T.; Lehmann, W.D.; Knappe, J.
    YfiD of Escherichia coli and Y06I of bacteriophage T4 as autonomous glycyl radical cofactors reconstituting the catalytic center of oxygen-fragmented pyruvate formate-lyase (2001), Biochem. Biophys. Res. Commun., 285, 456-462.
    View publication on PubMed

Activating Compound

Activating Compound Comment Organism Structure
Y06I autonomous glycyl radical cofactor, reconstituting the catalytic center of oxygen-fragmented enzyme Tequatrovirus T4
YfiD
-
Salmonella enterica subsp. enterica serovar Typhimurium
YfiD
-
Haemophilus influenzae
YfiD
-
Yersinia pestis
YfiD
-
Vibrio cholerae serotype O1
YfiD
-
Pasteurella multocida
YfiD
-
Escherichia coli
YfiD autonomous glycyl radical cofactor, reconstituting the catalytic center of oxygen-fragmented enzyme Escherichia coli

Crystallization (Commentary)

Crystallization (Comment) Organism
-
Escherichia coli

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
pyruvate + CoA Salmonella enterica subsp. enterica serovar Typhimurium
-
acetyl-CoA + formate
-
r
pyruvate + CoA Haemophilus influenzae
-
acetyl-CoA + formate
-
r
pyruvate + CoA Escherichia coli
-
acetyl-CoA + formate
-
r
pyruvate + CoA Tequatrovirus T4
-
acetyl-CoA + formate
-
r
pyruvate + CoA Yersinia pestis
-
acetyl-CoA + formate
-
r
pyruvate + CoA Vibrio cholerae serotype O1
-
acetyl-CoA + formate
-
r
pyruvate + CoA Pasteurella multocida
-
acetyl-CoA + formate
-
r

Organism

Organism UniProt Comment Textmining
Escherichia coli
-
-
-
Escherichia coli P09373 PFL, SwissProt accession number
-
Haemophilus influenzae
-
-
-
Pasteurella multocida
-
-
-
Salmonella enterica subsp. enterica serovar Typhimurium
-
-
-
Tequatrovirus T4
-
-
-
Vibrio cholerae serotype O1
-
-
-
Yersinia pestis
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
acetyl-CoA + formate
-
Escherichia coli pyruvate + CoA
-
r
pyruvate + CoA
-
Salmonella enterica subsp. enterica serovar Typhimurium acetyl-CoA + formate
-
r
pyruvate + CoA
-
Haemophilus influenzae acetyl-CoA + formate
-
r
pyruvate + CoA
-
Escherichia coli acetyl-CoA + formate
-
r
pyruvate + CoA
-
Tequatrovirus T4 acetyl-CoA + formate
-
r
pyruvate + CoA
-
Yersinia pestis acetyl-CoA + formate
-
r
pyruvate + CoA
-
Vibrio cholerae serotype O1 acetyl-CoA + formate
-
r
pyruvate + CoA
-
Pasteurella multocida acetyl-CoA + formate
-
r

Synonyms

Synonyms Comment Organism
PFL
-
Escherichia coli