Literature summary for 2.3.1.51 extracted from

Jasieniecka-Gazarkiewicz, K.; Demski, K.; Lager, I.; Stymne, S.; Banas, A.
Possible role of different yeast and plant lysophospholipid acyl-CoA acyltransferases (LPLATs) in acyl remodelling of phospholipids (2016), Lipids, 51, 15-23 .

Search for more literature for 2.3.1.51

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
microsome	-	Saccharomyces cerevisiae	-	-

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
oleoyl-CoA + 1-oleoyl-lysophosphatidic acid	Saccharomyces cerevisiae	-	CoA + 1,2-dioleoyl-sn-lysophosphatidic acid	-	r
oleoyl-CoA + 1-oleoyl-sn-lysophosphatidylethanolamine	Saccharomyces cerevisiae	-	CoA + 1,2-dioleoyl-sn-lysophosphatidylethanolamine	-	r

Organism

Organism	UniProt	Comment	Textmining
Saccharomyces cerevisiae	P33333	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
additional information	substrate specificity (towards different acyl acceptors) of the lysophospholipid:acyl-CoA acyltransferase in the forward reactions with [14C]18:1-CoA, assay optimization. Ratio between reverse and forward activities for different LPLATs for different phospholipids, overview	Saccharomyces cerevisiae	?	-	-
oleoyl-CoA + 1-oleoyl-lysophosphatidic acid	-	Saccharomyces cerevisiae	CoA + 1,2-dioleoyl-sn-lysophosphatidic acid	-	r
oleoyl-CoA + 1-oleoyl-lysophosphatidic acid	preferred substrate. Slc1 has a very high capacity of reversibility towards the PtdOH substrate	Saccharomyces cerevisiae	CoA + 1,2-dioleoyl-sn-lysophosphatidic acid	-	r
oleoyl-CoA + 1-oleoyl-sn-lysophosphatidylcholine	low activity, cf. EC 2.3.1.23. Slc1 has no detectable reverse reaction towards PtdCho substrate	Saccharomyces cerevisiae	CoA + 1,2-dioleoyl-sn-lysophosphatidylcholine	-	ir
oleoyl-CoA + 1-oleoyl-sn-lysophosphatidylethanolamine	-	Saccharomyces cerevisiae	CoA + 1,2-dioleoyl-sn-lysophosphatidylethanolamine	-	r
oleoyl-CoA + 1-oleoyl-sn-lysophosphatidylethanolamine	lower activity, cf. EC 2.3.1.121	Saccharomyces cerevisiae	CoA + 1,2-dioleoyl-sn-lysophosphatidylethanolamine	-	r

Synonyms

Synonyms	Comment	Organism
LPAAT	-	Saccharomyces cerevisiae
lysophosphatidic acid acyltransferase	-	Saccharomyces cerevisiae
lysophospholipid:acyl-CoA acyltransferase	-	Saccharomyces cerevisiae
More	cf. EC 2.3.1.121 and EC 2.3.1.23	Saccharomyces cerevisiae
Scl1	-	Saccharomyces cerevisiae

Temperature Optimum [°C]

Temperature Optimum [°C]	Temperature Optimum Maximum [°C]	Comment	Organism
30	-	assay at	Saccharomyces cerevisiae

pH Optimum

pH Optimum Minimum	pH Optimum Maximum	Comment	Organism
7.2	-	assay at	Saccharomyces cerevisiae

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Release 2023.1 (January 2023)