Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
membrane | - |
Saccharomyces cerevisiae | 16020 | - |
microsome | - |
Saccharomyces cerevisiae | - |
- |
mitochondrion | the presence of the enzyme in the mitochondrial fraction cannot be explained by the contamination of microsomes in this fraction | Saccharomyces cerevisiae | 5739 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Saccharomyces cerevisiae | - |
OC-2 | - |
Saccharomyces cerevisiae OC-2 | - |
OC-2 | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
acyl-CoA + 1-acyl-sn-glycerol 3-phosphate | i.e. lysophosphatidic acid, highly specific for 1-acyl-sn-glycerol 3-phosphate, catalyzes acylation of position 2 hydroxyl-group | Saccharomyces cerevisiae | CoA + 1,2-diacyl-sn-glycerol 3-phosphate | i.e. phosphatidic acid | ? | |
acyl-CoA + 1-acyl-sn-glycerol 3-phosphate | effect of substrate concentration | Saccharomyces cerevisiae | CoA + 1,2-diacyl-sn-glycerol 3-phosphate | i.e. phosphatidic acid | ? | |
acyl-CoA + 1-acyl-sn-glycerol 3-phosphate | the enzyme utilizes saturated and unsaturated acyl-CoAs at comparable rates | Saccharomyces cerevisiae | CoA + 1,2-diacyl-sn-glycerol 3-phosphate | i.e. phosphatidic acid | ? | |
acyl-CoA + 2-acyl-sn-glycerol 3-phosphate | the rate of CoA-liberation is much lower than with 1-acyl-sn-glycerol 3-phosphate | Saccharomyces cerevisiae | CoA + ? | - |
? | |
additional information | very broad specificity for acyl-CoAs, the enzyme does not seem to discriminate strictly the cis and trans configurations or the position of double bond in the fatty acyl moiety | Saccharomyces cerevisiae | ? | - |
? | |
oleoyl-CoA + 1-acyl-sn-glycerol 3-phosphate | - |
Saccharomyces cerevisiae | CoA + 1-acyl-2-oleoyl-sn-glycerol 3-phosphate | - |
? | |
palmitoyl-CoA + 1-acyl-sn-glycerol 3-phosphate | - |
Saccharomyces cerevisiae | CoA + 1-acyl-2-palmitoyl-sn-glycerol 3-phosphate | - |
? |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7 | 9 | broad | Saccharomyces cerevisiae |