Cloned (Comment) | Organism |
---|---|
gene tsc3 | Saccharomyces cerevisiae |
Protein Variants | Comment | Organism |
---|---|---|
additional information | tsc3 mutants show reduced enzyme activity, tsc3 is not required for expression, stability and membrane association of Lcb1p and Lcbp2 | Saccharomyces cerevisiae |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
microsome | membrane associated | Saccharomyces cerevisiae | - |
- |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
palmitoyl-CoA + L-serine | Saccharomyces cerevisiae | - |
CoA + 3-dehydro-D-sphinganine + CO2 | - |
ir |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Saccharomyces cerevisiae | - |
genes LCB1/TSC2, LCB2/TSC1, TSC3 | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
additional information | - |
activity in wild-type and tsc3 mutants | Saccharomyces cerevisiae |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
palmitoyl-CoA + L-serine | - |
Saccharomyces cerevisiae | CoA + 3-dehydro-D-sphinganine + CO2 | - |
ir |
Subunits | Comment | Organism |
---|---|---|
More | Lcbp1 and Lcp2 are 2 subunits of the enzyme, tightly associated and not stable independently, tsc3 protein is loosely associated to them | Saccharomyces cerevisiae |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
assay at | Saccharomyces cerevisiae |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
8.3 | - |
assay at | Saccharomyces cerevisiae |