Application | Comment | Organism |
---|---|---|
medicine | present study examines an association of slow N-acetyltransferase 2 profile caused by classical N-acetylation polymorphism and anti-tuberculosis drug-induced hepatotoxicity in patients from Southern Brazil. 254 Brazilian tuberculosis patients using isoniazid (INH), rifampicin (RMP), and pirazinamide (PZA) are tested in a prospective cohort study. Results demonstrate that HIV-positive patients that have the slow acetylation profile are significantly associated with a higher risk of developing hepatotoxicity due to anti-tuberculosis drugs | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | P11245 | - |
- |
Synonyms | Comment | Organism |
---|---|---|
arylamine N-acetyltransferase 2 | - |
Homo sapiens |
NAT2 | - |
Homo sapiens |