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Literature summary for 2.3.1.48 extracted from

  • Cano, A.; Pestana, A.
    Purification and properties of a histone acetyltransferase from Artemia salina, highly efficient with H1 histone (1979), Eur. J. Biochem., 97, 65-72.
    View publication on PubMed

Activating Compound

Activating Compound Comment Organism Structure
additional information requires free SH-groups Artemia salina

Inhibitors

Inhibitors Comment Organism Structure
Ca2+
-
Artemia salina
histone histone H1 acetylation is inhibited by all other histone fractions Artemia salina
K+ strong Artemia salina
Mg2+
-
Artemia salina
Mn2+
-
Artemia salina
Na+ strong Artemia salina

Localization

Localization Comment Organism GeneOntology No. Textmining
nucleus
-
Artemia salina 5634
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
170000
-
gel filtration, 0.2 M KCl Artemia salina
280000
-
10 mM Tris-HCl, gel filtration Artemia salina

Organism

Organism UniProt Comment Textmining
Artemia salina
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
Artemia salina

Source Tissue

Source Tissue Comment Organism Textmining
larva
-
Artemia salina
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
0.0014
-
purified enzyme Artemia salina

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
acetyl-CoA + histone histone H1 is a better substrate than H3 or H4 Artemia salina CoA + acetylhistone
-
?
acetyl-CoA + histone H1 histone H1 is a better substrate than H3 or H4 Artemia salina CoA + acetylhistone H1
-
?
acetyl-CoA + histone H3 histone H1 is a better substrate than H3 or H4 Artemia salina CoA + acetylhistone H3
-
?

Temperature Stability [°C]

Temperature Stability Minimum [°C] Temperature Stability Maximum [°C] Comment Organism
-
20 half-life: 20 h Artemia salina
40
-
half-life: 2 min Artemia salina

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
8.5
-
-
Artemia salina