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Literature summary for 2.3.1.43 extracted from

  • Furukawa, Y.; Nishida, T.
    Stability and properties of lecithin-cholesterol acyltransferase (1979), J. Biol. Chem., 254, 7213-7219.
    View publication on PubMed

General Stability

General Stability Organism
apo-A-1, albumin and lecithin-cholesterol vesicles stabilize Homo sapiens
inactivation at the air-water interface is prevented by buffered media of low ionic strength Homo sapiens
lecithin-cholesterol vesicles stabilize against inactivation to a lesser extent than apo-A-1 Homo sapiens
remarkably stable in buffers of very low ionic strength Homo sapiens

Metals/Ions

Metals/Ions Comment Organism Structure
additional information with lecithin-cholesterol vesicles as substrates in the presence of apo-A-1 the enzyme requires an ionic strength of approximately 0.05 for maximal activity Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
plasma
-
Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
phosphatidylcholine + sterol
-
Homo sapiens 1-acylglycerophosphocholine + sterol ester
-
r

Temperature Stability [°C]

Temperature Stability Minimum [°C] Temperature Stability Maximum [°C] Comment Organism
37
-
0.4 mM phosphate buffer, pH 7.4, ionic strength 0.001: stable up to 6 h, 39 mM phosphate buffer, pH 7.4, ionic strength 0.1: 90% loss of activity Homo sapiens