Activating Compound | Comment | Organism | Structure |
---|---|---|---|
apolipoprotein A-I | required for hydrolysis of ester linkage at carbon-2 position of phosphatidylcholine and for transesterification | Homo sapiens |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
65000 | - |
x * 65000, SDS-PAGE | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Purification (Comment) | Organism |
---|---|
- |
Homo sapiens |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
plasma | - |
Homo sapiens | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
additional information | - |
- |
Homo sapiens |
3.47 | - |
in cholesterol-lecithin vesicles activated with apolipoprotein A1 | Homo sapiens |
Storage Stability | Organism |
---|---|
4°C, low ionic strength buffer, under nitrogen, 4 weeks | Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | long-chain primary alcohols can act as acyl acceptors | Homo sapiens | ? | - |
? | |
additional information | enzyme hydrolyses ester linkage at carbon-2 position of phosphatidylcholine | Homo sapiens | ? | - |
? | |
phosphatidylcholine + sterol | wide specificity for acyl acceptor: sterols with a beta-configuration at carbon-3 and trans fused A /B rings | Homo sapiens | 1-acylglycerophosphocholine + sterol ester | - |
r | |
phosphatidylcholine + sterol | water as acyl acceptor: phospholipase activity | Homo sapiens | 1-acylglycerophosphocholine + sterol ester | - |
r |
Subunits | Comment | Organism |
---|---|---|
? | x * 65000, SDS-PAGE | Homo sapiens |