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Literature summary for 2.3.1.43 extracted from

  • Knipping, G.
    Isolation and properties of porcine lecithin:cholesterol acyltransferase (1986), Eur. J. Biochem., 154, 289-294.
    View publication on PubMed

Activating Compound

Activating Compound Comment Organism Structure
apolipoprotein A-I both human and pig ApoA-1 can activate pig LCAT in cholesterol-lecithin liposomes Sus scrofa

Inhibitors

Inhibitors Comment Organism Structure
apolipoprotein C-2 inhibitor in high concentration Sus scrofa

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
69000
-
x * 69000, SDS-PAGE Sus scrofa

Organism

Organism UniProt Comment Textmining
Sus scrofa
-
pig
-

Posttranslational Modification

Posttranslational Modification Comment Organism
glycoprotein 21% w/w carbohydrate, including hexoses, hexosamines and sialic acids Sus scrofa

Purification (Commentary)

Purification (Comment) Organism
phenyl-Sepharose and hydroxyapatite column chromatography Sus scrofa

Source Tissue

Source Tissue Comment Organism Textmining
plasma
-
Sus scrofa
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
0.15
-
in cholesterol-lecithin vesicles activated with porcine apolipoprotein A1 Sus scrofa

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information lecithin-cholesterol single bilayer vesicles as substrate Sus scrofa ?
-
?
phosphatidylcholine + sterol
-
Sus scrofa 1-acylglycerophosphocholine + sterol ester
-
r

Subunits

Subunits Comment Organism
? x * 69000, SDS-PAGE Sus scrofa