Any feedback?
Literature summary for 2.3.1.43 extracted from
- Mechanisms of action of lecithin-cholesterol acyltransferase (1986), Methods Enzymol., 129, 783-790.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| apolipoprotein A-I | most effective activator | Homo sapiens |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| plasma | - |
Homo sapiens | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| phosphatidylcholine + sterol | wide specificity for acyl acceptor: sterols with a beta-configuration at carbon-3 and trans fused A /B rings | Homo sapiens | 1-acylglycerophosphocholine + sterol ester | - |
r |  |
| phosphatidylcholine + sterol | water as acyl acceptor: phospholipase activity | Homo sapiens | 1-acylglycerophosphocholine + sterol ester | - |
r | |
| phosphatidylcholine + sterol | phosphatidylethanolamine, dimethylphosphatidylethanolamine, lecithins containing different acyl chain lengths and degrees of saturation | Homo sapiens | 1-acylglycerophosphocholine + sterol ester | - |
r | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| LAT | - |
- |
| LCAT | - |
- |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| apolipoprotein A1 | - |
Homo sapiens |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
