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Literature summary for 2.3.1.41 extracted from
- An unusual seed-specific 3-ketoacyl-ACP synthase associated with the biosynthesis of petroselinic acid in coriander (2001), Plant Mol. Biol., 47, 507-518.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| construction of a cDNA library from developing seeds, DNA sequence analysis, expression as His-tagged enzyme in Escherichia coli | Coriandrum sativum |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| cerulenin | strong | Coriandrum sativum |  |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| chloroplast | - |
Coriandrum sativum | 9507 | - |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| additional information | - |
amino acid sequence alignment | Coriandrum sativum |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 4-hexadecenoyl-[acyl-carrier protein] + malonyl-[acyl-carrier protein] | Coriandrum sativum | reaction is part of petroselinic acid biosynthesis, synthase IV | 3-oxo-6-octadecenoyl-[acyl-carrier protein] + CO2 + [acyl-carrier protein] | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Coriandrum sativum | - |
seed plastid-specific isoform with similarities to synthase I type | - |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| recombinant His-tagged seed-specific isoform from E. coli | Coriandrum sativum |
Reaction
| Reaction | Comment | Organism | Reaction ID |
|---|---|---|---|
| an acyl-[acyl-carrier protein] + a malonyl-[acyl-carrier protein] = a 3-oxoacyl-[acyl-carrier protein] + CO2 + an [acyl-carrier protein] | active site cysteine | Coriandrum sativum |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| seed | germinating | Coriandrum sativum | - |
| seed | specific isoform | Coriandrum sativum | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 4-hexadecenoyl-[acyl-carrier protein] + malonyl-[acyl-carrier protein] | best substrate, highly specific for | Coriandrum sativum | 3-oxo-6-octadecenoyl-[acyl-carrier protein] + CO2 + [acyl-carrier protein] | - |
? | |
| 4-hexadecenoyl-[acyl-carrier protein] + malonyl-[acyl-carrier protein] | reaction is part of petroselinic acid biosynthesis, synthase IV | Coriandrum sativum | 3-oxo-6-octadecenoyl-[acyl-carrier protein] + CO2 + [acyl-carrier protein] | - |
? | |
| hexadecanoyl-[acyl-carrier protein] + malonyl-[acyl-carrier protein] | - |
Coriandrum sativum | 3-oxooctadecanoyl-[acyl-carrier protein] + CO2 + [acyl-carrier protein] | - |
? | |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 7.5 | - |
assay at | Coriandrum sativum |
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Release 2023.1 (January 2023)
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