Protein Variants | Comment | Organism |
---|---|---|
R606A | the mutation severely impairs the malonyl transfer reaction, while leading to a kinetic improvement of the transferase activity for acetyl-CoA | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
acetyl-CoA + an [acyl-carrier protein] | Homo sapiens | - |
CoA + an acetyl-[acyl-carrier protein] | - |
? | |
malonyl-CoA + an [acyl-carrier protein] | Homo sapiens | - |
CoA + a malonyl-[acyl-carrier protein] | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | P49327 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
acetyl-CoA + an [acyl-carrier protein] | - |
Homo sapiens | CoA + an acetyl-[acyl-carrier protein] | - |
? | |
malonyl-CoA + an [acyl-carrier protein] | - |
Homo sapiens | CoA + a malonyl-[acyl-carrier protein] | - |
? |
Synonyms | Comment | Organism |
---|---|---|
FAS | - |
Homo sapiens |
fatty acid synthase | - |
Homo sapiens |
MAT | malonyl-acetyl transferase domain of fatty acid synthase | Homo sapiens |