Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 2.3.1.39 extracted from

  • Kumar, P.; Koppisch, A.T.; Cane, D.E.; Khosla, C.
    Enhancing the modularity of the modular polyketide synthases: transacylation in modular polyketide synthases catalyzed by malonyl-CoA:ACP transacylase (2003), J. Am. Chem. Soc., 125, 14307-14312.
    View publication on PubMed

Application

Application Comment Organism
biotechnology the enzyme is active as part of a recombinant engineered modular enzyme complex system for modified and designed polyketid synthesis, overview Streptomyces coelicolor

Cloned(Commentary)

Cloned (Comment) Organism
expression in Escherichia coli strain BL21(DE3) Streptomyces coelicolor

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
malonyl-CoA + [acyl-carrier protein] Streptomyces coelicolor
-
CoA + malonyl-[acyl-carrier protein]
-
?

Organism

Organism UniProt Comment Textmining
Streptomyces coelicolor
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
malonyl-CoA + [acyl-carrier protein]
-
Streptomyces coelicolor CoA + malonyl-[acyl-carrier protein]
-
?
malonyl-CoA + [acyl-carrier protein] enzyme is active with a type II [acyl-carrier protein] from a recombinant modular polyketid synthase with inactivated acyl transferase domain, overview Streptomyces coelicolor CoA + malonyl-[acyl-carrier protein]
-
?

Synonyms

Synonyms Comment Organism
malonyl-CoA:ACP transacylase
-
Streptomyces coelicolor
MAT
-
Streptomyces coelicolor