Inhibitors | Comment | Organism | Structure |
---|---|---|---|
additional information | inhibition of malonyl-enzyme intermediate formation by p-chloromercuribenzoate, reversible by 2-mercaptoethanol, prevented by preincubation with malonyl-CoA; inhibition of malonyl-enzyme intermediate formation by phenylmethanesulfonyl fluoride, malonyl-CoA protects; pH-dependent inhibition of malonyl-enzyme intermediate formation by N-ethylmaleimide | Escherichia coli |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Escherichia coli | - |
- |
- |
Reaction | Comment | Organism | Reaction ID |
---|---|---|---|
malonyl-CoA + an [acyl-carrier protein] = CoA + a malonyl-[acyl-carrier protein] | isolation and characterization of an enzyme-intermediate | Escherichia coli |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
malonyl-CoA + acyl-carrier protein | acetyl-CoA cannot replace malonyl-CoA | Escherichia coli | CoA + malonyl-[acyl-carrier protein] | - |
? | |
malonyl-CoA + acyl-carrier protein | participation of a malonyl-enzyme intermediate in the reaction | Escherichia coli | CoA + malonyl-[acyl-carrier protein] | - |
? |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
25 | - |
assay at | Escherichia coli |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
6 | 7.5 | for the malonyl-enzyme intermediate formation. The enzyme accepts malonyl groups from either malonyl-CoA or malonyl-acyl-carrier-protein to form the enzyme-intermediate, the malonyl group of the intermediate can be transferred to both CoA and acyl-carrier-protein | Escherichia coli |
pH Stability | pH Stability Maximum | Comment | Organism |
---|---|---|---|
additional information | - |
of malonyl-enzyme intermediate | Escherichia coli |