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Literature summary for 2.3.1.37 extracted from

  • Hunter, G.A.; Zhang, J.; Ferreira, G.C.
    Transient kinetic studies support refinements to the chemical and kinetic mechanisms of aminolevulinate synthase (2007), J. Biol. Chem., 282, 23025-23035.
    View publication on PubMed

Organism

Organism UniProt Comment Textmining
Mus musculus
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Reaction

Reaction Comment Organism Reaction ID
succinyl-CoA + glycine = 5-aminolevulinate + CoA + CO2 5-aminolevulinate synthase operates under the stereoelectronic control predicted by Dunathan’s hypothesis Mus musculus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
succinyl-CoA + glycine 5-aminolevulinate synthase operates under the stereoelectronic control predicted by Dunathan’s hypothesis Mus musculus 5-aminolevulinate + CoA + CO2
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Synonyms

Synonyms Comment Organism
mALAS-2 mature form of the murine erythroid specific isoform of aminolevulinate synthase Mus musculus