Any feedback?
Literature summary for 2.3.1.37 extracted from
- Yeast 5-aminolevulinate synthase provides additional chlorophyll precursor in transgenic tobacco (1997), Plant J., 12, 169-178.
Application
| Application | Comment | Organism |
|---|---|---|
| nutrition | enzyme expressed in transgenic Nicotiana tabacum plants demonstrate functional complementation in the chlorophyll biosynthesis and open strategies for producing tolerance against inhibitors of the C5 pathway | Saccharomyces cerevisiae |
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| fusion protein of enzyme and plastid-targeting small subunit of ribulose bisphosphate carboxylase for construction of transgenic plants | Saccharomyces cerevisiae |
Protein Variants
| Protein Variants | Comment | Organism |
|---|---|---|
| additional information | construction of transgenic plants of Nicotiana tabacum wild-type and mutant deficient in chlorophyll biosynthesis expressing the enzyme targeted to the plastids, functional complementation of the mutant, regulation | Saccharomyces cerevisiae |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| succinyl-CoA + glycine | Saccharomyces cerevisiae | key enzyme in tetrapyrrole biosynthesis | 5-aminolevulinate + CoA + CO2 | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Saccharomyces cerevisiae | - |
- |
- |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| additional information | - |
enzyme expressed in transgenic tabacco plants | Saccharomyces cerevisiae |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| succinyl-CoA + glycine | - |
Saccharomyces cerevisiae | 5-aminolevulinate + CoA + CO2 | - |
? | |
| succinyl-CoA + glycine | key enzyme in tetrapyrrole biosynthesis | Saccharomyces cerevisiae | 5-aminolevulinate + CoA + CO2 | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| ALA-S | - |
Saccharomyces cerevisiae |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| pyridoxal 5'-phosphate | required | Saccharomyces cerevisiae | |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
