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Literature summary for 2.3.1.37 extracted from
- Extraction and characterization of delta-aminolevulinate synthetase (1987), Comp. Biochem. Physiol. B, 87, 607-613.
No PubMed abstract available
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| additional information | 1-2 low molecular-weight compounds which stimulate or stabilize activity found by dialysis of crude extract | Rhodopseudomonas palustris |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| delta-aminolevuinate | product inhibition | Rhodopseudomonas palustris |  |
| additional information | cysteine, glutathione, cystine or 2-mercaptoethanol diminishes activity in presence of 5-aminolevulinate | Rhodopseudomonas palustris |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| additional information | - |
additional information | - |
Rhodopseudomonas palustris |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 61000 | 65000 | - |
Rhodopseudomonas palustris |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rhodopseudomonas palustris | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| cell culture | - |
Rhodopseudomonas palustris | - |
Storage Stability
| Storage Stability | Organism |
|---|---|
| -15°C, not stable | Rhodopseudomonas palustris |
| 0-4°C, 18 h stable | Rhodopseudomonas palustris |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| succinyl-CoA + glycine | absolute requirement for glycine | Rhodopseudomonas palustris | 5-aminolevulinate + CoA + CO2 | - |
? | |
| succinyl-CoA + glycine | absolute requirement for succinyl-CoA | Rhodopseudomonas palustris | 5-aminolevulinate + CoA + CO2 | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| monomer | 1 * 61000-65000 | Rhodopseudomonas palustris |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 37 | - |
- |
Rhodopseudomonas palustris |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 7.5 | - |
- |
Rhodopseudomonas palustris |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| pyridoxal 5'-phosphate | - |
Rhodopseudomonas palustris | |
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