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Literature summary for 2.3.1.37 extracted from
- Human delta-aminolevulinate synthase: assignment of the housekeeping gene to 3p21 and the erythroid-specific gene to the X chromosome (1990), Genomics, 7, 207-214.
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| succinyl-CoA + glycine | Homo sapiens | rate-limiting enzyme of heme biosynthesis | 5-aminolevulinate + CoA + CO2 | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| erythrocyte | enzyme in erythrocytes is genetically distinct from that in other tissue | Homo sapiens | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| succinyl-CoA + glycine | - |
Homo sapiens | 5-aminolevulinate + CoA + CO2 | - |
? | |
| succinyl-CoA + glycine | rate-limiting enzyme of heme biosynthesis | Homo sapiens | 5-aminolevulinate + CoA + CO2 | - |
? | |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| pyridoxal 5'-phosphate | - |
Homo sapiens | |
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Release 2023.1 (January 2023)
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